Cornell University BIOG 1105-1106
Unit 5: Demos

Unit 5: Immunology and Cancer.

An excerpt from Common Cold by Ogden Nash:

Go hang yourself, you old M.D,!
You shall not sneer at me.
Pick up your hat and stethoscope,
Go wash your mouth with laundry soap;
I contemplate a joy exquisite
In not paying you for your visit.
I did not call you to be told
My malady is a common cold.

By pounding brow and swollen lip;
By fever's hot and scaly grip;
By those two red redundant eyes
That weep like woeful April skies;
By racking snuffle, snort, and sniff;
By handkerchief after handkerchief;
This cold you wave away as naught
Is the damnedest cold man ever caught!

Bacilli swarm within my portals
Such as were ne'er conceived by mortals,
But bred by scientists wise and hoary
In some Olympic laboratory;
Bacteria as large as mice,
With feet of fire and heads of ice
Who never interrupt for slumber
Their stamping elephantine rumba.

Objective 1:

How inflammation works (interactive animation from Time magazine)
Immunology animation (optional)

Objective 9:

Complement system (9c) (much of this is supplemental)
Be the phagocyte!  Play the Immune System Defender Game
Immune response video (right click to download here or watch DVD in study center)
Immune response handout to accompany video

Objective 10:

The role of interleukins in the defensive response (10c)

Objective 11:

Booster shots and the role of memory cells (11b)
See optional links below for more information on vaccines and immunology
Poultry eggs may yield snake antivenin (optional)

Objective 12:

Autoimmune diseases result from a failure of "self-tolerance" (optional)
Multiple Sclerosis (optional)
Rethinking MS: multiple sclerosis may not be an autoimmune disease after all.
Lupus (optional)
Type-1 Diabetes (optional)
Publicly accessible MHC database for transplant / donor matching (optional)

Objective 13:

HIV and helper T cells
See optional links below for more information on HIV / AIDS

Objective 14:

What permits metastasis? (14b)
Scientific American: How Cancer Arises (available in Study Center; PDF available on Blackboard)

Objective 15:

Telomeres (15d)
Fix Those Genes or Else: defects in DNA proofreading can prompt tumors (optional)

Objective 16:

Scientific American: How Cancer Spreads (available in Study Center; PDF available on Blackboard)

Objective 17:

Risk factors for cancer
Immunotherapy for cancer (optional)
Learn more (from the American Cancer Society)
See optional links below for more information on cancer

Objective 18:

American Scientist: DNA Vaccines as Cancer Treatment (available in Study Center; PDF available on Blackboard)
HPV Vaccine: Info from the CDC
Cancer Vaccines (optional)
Scientific American: (available in Study Center; PDF available on Blackboard) (optional)

Optional Supplementary Material:

© 2010 | BIOG 1105-1106