Unit 3: Control of Gene Expression and Animal Development.

"If you give me the coding sequences of a chimp and the regulatory sequences of a mouse, I'll give you a mouse." - unknown geneticist.

Objective 3:

Operon Tutorial
lac operon animation
Induction of the lac operon

Objectives 4 & 5:

Positive v. negative control of prokaryotic gene transcription

Objective 6:

Transcription of eukaryotic vs. prokaryotic genomes (6c)

Objective 7:

How Does Methylation Control Synthesis of Proteins?
You are what your grandmother ate - diet linked to methylation ^(optional)
Genetic Imprinting: The Battle of the Sexes - Reloaded ^(optional)
Genome biology: She moves in mysterious ways - The human X chromosome is a study in contradictions. The detailed sequence of the X, and a survey of inactivated genes in females, help to illuminate this unique 'evolutionary space'.
Unexpressed but Indispensable: The (non-coding) DNA Sequences that Control Development. ^(optional)

Objective 9:

optional:

Diagram showing how Dolly was made (from Liem et al. Functional Anatomy of the Vertebrates, 3rd ed.)
Give the dog a clone
ViaGen: Gene Banking and Cloning of Exceptional Pets

Objective 14:

Yolk content and cleavage in human eggs (14c)
Zygote and morula (14d):
Zygotes: sea urchin, frog (zygote upper left, morula bottom right)

Objective 16:

Notochord development (16a)
Neural crest cells (16d):
Formation and fate of neural crest cells (16d)
Scientists Hatch a Few Odd Birds  (optional)
Somite development (16e)

Objective 17:

Comparative development (17b)

Objectives 19 & 20:

Determinate v. indeterminate cleavage & embryonic induction

Slides

Unit 3 Slides (accompanying text can be found in your Survival Manual on pages 57-59.)