Cornell University BIOG 1105-1106
Unit 3: Demos

Objective 3:

Operon Tutorial (optional, but helpful!)
Repression of the trp operon
lac operon (Jacob/Monod model) animation from Campbell Biology
Induction of the lac operon

Objectives 4 & 5:

Positive v. negative control of prokaryotic gene transcription

Objective 6:

Transcription of eukaryotic vs. prokaryotic genomes (6c)

Objective 7:

How Does Methylation Control Synthesis of Proteins?
You are what your parents ate - diet linked to methylation (optional)
Genetic Imprinting: The Battle of the Sexes - Reloaded (optional)
Genome biology: She moves in mysterious ways - The human X chromosome is a study in contradictions. The detailed sequence of the X, and a survey of inactivated genes in females, help to illuminate this unique 'evolutionary space'.
Unexpressed but Indispensable: The (non-coding) DNA Sequences that Control Development. (optional)

Objective 9:

optional:

Human clone produces stem cells  ... Or not?  Evidence found that data were fraudulent
Diagram showing how they made Dolly (from Liem et al. Functional Anatomy of the Vertebrates, 3rd ed.)
Give the dog a clone
ViaGen: Gene Banking and Cloning of Exceptional Pets

Objective 15:

Yolk content and cleavage in human eggs (15c)
Zygote and morula (15d):
Zygotes: sea urchin, frog (zygote upper left, morula bottom right)

Objective 17:

Notochord development (17a)
Neural crest cells (17d):
Formation and fate of neural crest cells - also see p.998 in Campbell
Scientists Hatch a Few Odd Birds  (optional)
Somite development (17e)

Objective 18:

Comparative development (18b)

Objectives 20 & 21:

Determinate v. indeterminate cleavage & embryonic induction

Slides

Unit 3 Slides (accompanying text can be found in your Survival Manual on pages 59-61.)

Somite Development

Somites, sometimes called paraxial mesoderm, are segments or blocks of mesoderm that form lateral to the notochord. Somites are arranged serially along both sides of a developing embryo and each somite can be divided into three regions from lateral to medial - the dermatome, sclerotome, and myotome. The superficial dermatome gives rise to the dermis, the deep layers of the skin. The middle layer, the sclerotome, gives rise to the vertebral column. Finally, the inner-most layer, the myotome, gives rise to skeletal muscles and the bones of the appendages.

Fig. 47-11c from Campbell, 6th ed. Note the somites in the lateral view of the embryo shown above right.

 

© 2010 | BIOG 1105-1106